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Sankara Nethralaya
Sankara Nethralaya
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Centre For Bioinformatics
Research
Funded Projects
Studies on Toxoplasma gondii Ron group of proteins for therapeutic intervention in Toxoplasmosis (DBT)
Design and Development of Carbonic Anhydrase Inhibitors (ICMR)
Development of Fatty Acid Synthase Inhibitors towards modulation of Retinoblastoma (DBT)
Next Generation Sequencing data analysis of Ocular Pathogens (ICMR)
Design and Development of ODC inhibitors (CSIR)
Systems Biology based drug target identification in Chlamydia trachomatis (DST-SERB)
Development of ROCK1 inhibitors (manpower funded by DBT)
 
 
 
 
 
 
 
 
 
Collaborative research as a Core Facility serving other Departments:
Design of peptide carrier molecules targeting fungal keratitis (Nanobiotechnology)
Structure Function relationship studies of PRR4 protein (Biochemistry)
Structure Function relationship studies on PON2 protein (Biochemistry)
Binding mode analysis of Fatty acids with therapeutically important proteins (Biochemistry)
Molecular modeling and Simulation studies of Aptamers and its molecular interactions (Nanobiotechnology& Pathology)
NGS based Variant Analysis of different ocular genetic disorders (Genetics)
Structure-function relationship studies of mutational impact on Retinoschisin- 1 (Genetics)
NGS Data Analysis of Ocular Pathogens& Mycobacterium tuberculosis (Microbiology)
Structure prediction of Lysyl oxidase using Insilico modeling techniques (Biochemistry)
Comparative study of LOX and other amine oxidases (Biochemistry)
Insilico mutation impact analysis in UL54 gene of hCMV (Microbiology)
Diabetic Retinopathy Microarray Analysis Project ( Genetics)
Glaucoma Genomewide Association Studies (GWAS) (Genetics)
Structural studies on proteins of Ocular therapeutic interest(Biochemistry)
Structure-function studies of the impact of mutations in Mycobacterium tuberculosis proteins (microbiology)
Rule based siRNA&Primer design of SPARC and Copper Transporter Receptor 1.(Biochemistry)
Mutational analysis of Pyrazinamide (PZA) of Mtb using structural bioinformatics approaches (Microbiology)
Structural analysis of CYP4V2 mutations (Genetics)
Structural analysis of SLC4A11mutations (Genetics)
Functional characterization of novel mutations in UL54 of ganciclovir resistant HCMV strain using structural analysis (Microbiology)
Design of SiRNA for copper binding proteins using Bioinformatics tools (Biochemistry)
Structure function analysis of 88KDa protein (Biochemistry)
Characterization of Hypothetical proteins present in tear (Biochemistry)
Insilico modeling and docking studies of Glutamate cysteine ligase (Biochemistry)
Identification of various binding regions/ residues in Osteonectin, PEDF and Decorin (Biochemistry)
Structural and functional analysis of Serum paraoxonase 2 using Insilico strategies (Biochemistry)
Identification of anti-angiogenic peptides in small Leucine rich repeats (Biochemistry)
Identification of Transcription factor Binding sites (CellBiology)
Structural Domain analysis of RIM protein (Genetics)
Structural analysis of RPE 65 mutations(Genetics)